86 INFLUENCE OF FOOD PRESERVATIVES ON HEALTH. 



recurrence of the ill feelings above referred to, and the quantity of 

 the preservative is diminished to one-fourth of a gram. On the 12th 

 of April decided symptoms of illness are continued, and by reason of 

 these symptoms, which persist for several days, the administration 

 of the preservative is omitted from the 12th to the 23d, inclusive, 

 although during this period No. 14 is able to appear each day, but is 

 feeling very badly. On April 24 the symptoms of malaise and depres- 

 sion have mostly passed away, and the administration of the preserva- 

 tive is again commenced, the quantity being one-fourth of a gram. 

 This is increased on the 25th of April to one-half a gram and continues 

 without change to May 1, inclusive. No noted disturbances are pro- 

 duced in the system during this last period of the administration of 

 the preservative. The temperature on the 30th, the day preceding 

 the last of the administration of the preservative, is almost normal, the 

 pulsations likewise normal, and the weight of the body 50.8 kilograms. 

 From May 2 to June 20, inclusive, one-half gram is given daily, 

 except on May 4, May 13, and June 9, when none is given. Dur- 

 ing this period the body conditions continue about in statu quo. There 

 is one instance where the temperature rises a trifle above the normal 

 during this period, but only for a short time. The weight of the body 

 on the 27th of June is 50.6 kilograms. There is a slight febrile attack 

 during the remaining three days, which reaches quite a degree of inten- 

 sity on the last day of observation, namely, June 29, when the tem- 

 perature rises to 100.4 F. and the pulsations to 104 per minute. The 

 result of these three days of illness, supervening upon almost a month 

 of good health, is to reduce the final weight to 48.7 kilograms. 



A general summar} r of the data of No. 14 would seem to indicate a 

 slight tendency on the part of the preservative, though used in small 

 quantities, to induce a feeling of depression, lack of appetite, and 

 general malaise. This is indicated on several occasions, as before 

 described, where it is not quite possible to connect these feelings with 

 abnormal conditions due to other sources. In general, however, the 

 data obtained on this subject are also unsatisfactory, owing to a rather 

 low degree of vitality, a tendency to febrile excitement, and other 

 conditions evidently riot connected in any way with the preservative 

 employed. While the data which have been collected in the case of 

 both No. 13 and No. 14 are not at all conclusive, and, as has been 

 already stated, are in many respects indecisive, two general con- 

 clusions may be drawn therefrom: First, that the effects of small doses 

 of the preservative over an extended period are not manifest by any 

 disturbance of a notable character; second, in so far as the disturbances 

 noted can be attributed to the preservative they are of an unfavorable 

 nature. 



