BORIC ACID AND BOKAX. 



171 



there was an apparent decrease, but this practically was accounted for 

 by the very great volume of urine secreted on the first day. 



In general it appears that a larger quantity of solids was excreted 

 during this period than normally. The quantity of common salt 

 excreted of course is not significant unless compared with the quantity 

 administered. It is largest in the case of No. 12, amounting to a mean 

 of 17.408 grams per day. It is smallest in the case of No. 11, where 

 the average quantity per day is 8.730 grams. 



In general it may be said that the data are not decisive in respect of 

 any influences of the increasing amount of preservative on the char- 

 acter of the excretion, with the possible exception of showing a tend- 

 ency to increased volume with corresponding decreased specific 

 gravity. On the whole, however, the quantity of solids excreted 

 appears to be larger than normal. 



SERIES III. 



The average daily volume of the urine of No. 1 during the fore period 

 is 931 cc, the average specific gravity, 1.0287; the average daily- amount 

 of total solids, 65.124 grams, and the average daily amount of common 

 salt excreted in the urine, 11.133 grams. (See Table XXXV, p. 185.) 

 There is a slight diminution in the volume of the urine during the 

 first preservative subperiod and an-increase in its volume during the 

 second and third subperiods, the mean volume for the three subperiods 

 being ver} 7 little more than that for the fore period. There is a marked 

 increase in volume in the after period. 



These data show that in the case of No. 1 the preservative has no 

 tendency whatever to produce diuresis, but is inclined to produce the 

 opposite results. The specific gravity rises a little during the first 

 preservative subperiod, but lowers during the second and third sub- 

 periods, the average for the three subperiods showing a diminished 

 specific gravity as compared with the fore period. There is a marked 

 decrease in the specific gravity during the after period, caused to some 

 extent, but not entirely, by the increased volume. The total solids 

 eliminated are also decreased during the preservative period, although 

 practically all of the preservative given is eliminated by the urine. 

 This tendency to decrease is also continued during the after period, 

 indicating a persistence on the part of the preservative to interfere 

 with those metabolic processes which result in the supply of solid 

 matter to the urine. In r^ard to common salt, it may be said that 

 the amount administered is assumed to be practically constant through- 

 out the period of observation. The effect of the preservative is noticed 

 in the diminished excretion of common salt, and this tendenc} 7 to 

 diminish excretion is continued throughout the after period. 



In the case of No. 2 there is a slight decrease in the volume of 

 urine during the administration of the preservative, and this decrease 



