GLANDULAR PREPARATIONS. 



49 



Pepsin is an extract of the fresh endogastrium of the hog, and consists principally 

 of a proteolytic ferment. 



Suprarenalum Siccum consists of the cleaned, dried, powdered suprarenal glands 

 of various food animals. It should contain not less than 0.4% of -epinephrine, the 

 active pressor principle of the gland. In the British Pharmacopoeia, a i-iooo solution 

 in N. S. is official, and is a convenient way of using the drug. 



Thyroideum Siccum consists of the cleaned, dried, and powdered thyroid glands 

 of food animals, and contains not less than 0.17% of iodine in thyroid combination. 



Properties: 



Label 12 test-tubes A to L. In A, B, G and H place 6 mils each freshly prepared 

 starch paste ; in C, D, I and J place 6 mils each skimmed milk ; in E, F, K and L place 

 6 mils olive oil. To A, C, E, G, I and K add 10 mg. each Na9COs ; to the others, add 0.2 

 mil each dil. HC1. To A to F inclusive add 5 mg. each pepsin ; to the others add 10 mg. 

 each pancreatin. Place all in a water bath kept at constant 40 C. After 30 minutes 

 examine each test-tube, and note whatever changes may have occurred. Make appro- 

 priate tests of samples from each. Repeat after a further hour of enzyme activity. 



