226 CAMPHOR. PHOSPHORUS. 



CAMPHOR (continued). 



Symptoms. 



Medicinal Dose. Large Doses. Toxic Doses. 



Hot, bitter taste. Headache, confusion. Drowsiness. 



Warm sensation in stom- Excitement. Unconsciousness. 



ach. Slowing of pulse. Stupor. 



Feeling of comfort. Nausea and vomiting. Respiratory failure. 



Flushing of skin. 



Hallucinations. 



Deliria. 



Stupor. 



Unconsciousness. 



Therapeutics. 



Camphor was formerly much used as an antispasmodic and nerve sedative. Its 

 principal use today is for counterirritation, giving best results when made up in strong 

 (50%) alcoholic solutions. For tender skins a 10% solution in oil may be used. 



Dosage. 



Spiritus Camphorse (10%), 0.3 to 2 mils. 



PHOSPHORUS. 



Phosphorus (P = 30.77) is a non-metallic element, usually obtained from bones 

 and certain minerals. 



Pharmacodynamics. 



Central Nervous System. Little changed. 



Muscular System. Not affected except by the general tendency to fatty degen- 

 eration. 



Respiration. No known effect. 



Heart. Not affected, except in toxic doses. 



Blood-pressure doesn't seem to be affected in any way. 



Alimentary Tract. Phosphorus induces a fatty infiltration of the epithelial cells. 

 with sequent intercellular fibrosis. Bile salts are decreased ; bile pigments increased at 

 first, but later decreased; glycogen and lecithin reduced; increase of autolytic ferment, 



Secretory Glands. Fatty degeneration of the epithelium of the kidney. 



Metabolism. Phosphorus is a stimulant to the production of osteoblasts and of 

 erythrocytes. It increases katabolism, especially of the liver, where a fatty infiltra- 

 tion soon ensues followed by intercellular fibrosis. 



Temperature varies, sometimes rising, sometimes falling. 



Absorption. Phosphorus is absorbed with great difficulty, except when in a state 

 of minute subdivision. 



Excretion is obscure ; some by kidneys, and some by the lungs. 



Local Action. May ignite and produce bad burns. 



