16 Harry C. Schmeisser. 



normal to the bone-marrow, and when extramedullar is typical of 

 leukaemia. Lymphocytes and polymorphs were strikingly decreased. 

 Of the latter those with red granules and the mast cell were rare. 

 Mitoses of the large mononuclear were common. The red blood cells 

 appeared to be poor in haemoglobin and showed anisocytosis, 

 poikilocytosis and polychromatophilia. These cytoplasmatic changes 

 were usually associated with an increase in the size of the nucleus. 

 Premature red blood cells, normoblasts and megaloblasts were present in 

 large numbers. 



Differential Count, 300 Cells. 



Per cent. 



Polymorphonuclear with eoslnophilic rods 8 



Polymorphonuclear with eosinophilic granules 



Lymphocyte 2 



Large mononuclear cell 30 



Mast cell 



Monuclear myelocyte with eosinophilic granules 52 



Unclassified cells 8 



100 

 AUTOPSY PEOTOCOL. 



The animal was of medium size ; the weight was not taken. 



External Appearance. Comb, featherless area about eyes, and 

 wattles of an ash color. Buccal mucous membrane and conjunctivas, 

 very pale. Anterior chamber of left eye filled with an old blood- 

 clot. Eight eye normal. A moderately firm slightly nodular tumor, 

 3.7 x 2 x 1.5 cm., occupied the triangular space on the left side of 

 head between the angle of the mouth, ear and angle of the lower jaw, 

 extending below the ramus of the latter. Subcutaneous fat was 

 practically absent. Emaciation was extreme and there was marked 

 muscular atrophy. A second, slightly smaller tumor, 1.7 x 1 x 1 cm., 

 was found just inside the ramus and below the orbit, apparently 

 communicating over the ramus with the first growth and continuous 

 below with a slightly larger, third mass.* 



Cervical Lymph-glands. Somewhat enlarged. Lobulation indis- 

 tinct. 



* A more detailed description and study of these tumors will be reserved 

 for a future communication. 



