262 MATERIA MEDIC A AND THERAPEUTICS. 



3. Infusum Cinchonse Flavse. 1 in 20. Dose, 1 to 2 fl.oz. 



4. Tinctura Cinchona Flavae. 1 in 5. Dose, % to 2 fl.dr. 



5. Quinise Sulphas. 



B. O/ A<? -P#& -Bar& (Cinchona Pallida] : 



1. Tinctura Cinchona? Composita. Pale Bark, Bitter-Orange 

 Peel, Serpentary, Saffron, Cochineal, and Proof Spirit. 

 1 in 10. Dose, % to 2 fl.dr. 



c. Of the Red ark there are no officinal preparations. 

 D. Of the Lance-leaved Cinchona Bark : Quiniae Sulphas. 



ACTION AND USES. 



The action and uses of the Cinchona harks will he described 

 along with those of Quinia, their most important active prin- 

 ciple. 



Sulphas SULPHATE OF QUINIA. (C^ 



H 24 N 2 O 2 ) 2 H 2 S0 4 .7H 2 0. The sulphate of an alkaloid, 

 prepared from yellow Cinchona bark, and from, the 

 bark of Cinchona lancifolia, Mutis. 



Source. Made hy (1) exhausting the bark with Diluted 

 Hydrochloric Acid ; (2) precipitating the Quinia with Solution of 

 Soda; (3) dissolving this in Diluted Sulphuric Acid; and (4) 

 crystallising out. 



Characters. Filiform silky snow-white crystals, with an 

 intensely bitter taste. Solubility, 1 in 576 of water : 60 gr. 

 require 60 min. of diluted sulphuric, or 100 min. of diluted phos- 

 phoric acid ; and 66 gr. require 60 min. of diluted nitric acid 

 for solution in two ounces of distilled water. 12 gr. = 1 oz. 

 of good bark. 



Impurities. Sulphates of the other cinchona alkaloids, and 

 of lime, chalk, magnesia ; starch, boracic acid, etc. ; detected by 

 the quantitative test given above. Salicin; which gives blood- 

 red with sulphuric acid. 



Incompatible*. Alkalies and their carbonates, astringent 

 infusions. Nitric acid alone makes a clear mixture with sul- 

 phate of quinia. 



Dose. 1 to 5 gr. as a tonic ; larger doses as an antipyretic 

 and antiperiodic. 



Preparations. 



1. Ferri et Quiniss Citras. 16 in 100. Dose, 5 to 10 gr. 



2. Pilula Quinise. 1 with of Confection of Hips. Dose, 2 to 



10 gr. 



