METABOLISM OF ORGANIC AND INORGANIC 

 PHOSPHORUS. 



REVIEW OF THE LITERATURE. 



Much \\ork ha- already heen done on phosphorus metaholi-m. 

 hoili in regard to the inorganic and organic forms of phosphorus, and 

 many in\ e>t iirat ion- have hern recorded showing the advantages of 

 the varioii- organic forms, such as lecithin, irlveero-phosphoric acid, 

 phytin. etc. Mo>t of this work ha- heen done abroad, although 

 some ha- heen puhlished in this country, notahly the ivscaivhe- ,.f 

 Jordan. Patten, and Hat;; Mendel and I'mh-rhill ;'' and Le Here 



and < :ued nd\i-ahle. therefore, to present a irenem! 



survey of the Contributions previously made on this mooted question. 



PHOSPHORUS COMPOUNDS. 



In -peaking of pho-phorn- compounds. Bimire ' -tales that cer- 

 tain of them pmhahly -hould h mic food 



-uh-taiice- fi.r man: aUo that in all animal and veiretahle tissues, 

 in every cell are found t\\o emnplrx organic compounds which are 

 ri<-h in pho-phni-. namely, the lecithins and the nuclein^. 



According to the recent recommendations of the joint commi; 



of the American l*h\ -ioL.^ical Society and the American Society 

 of Hio|,,._ri-al Cliemi-t> on protein iK.menclat lire, the word " jn-oteid " 

 should he ahandone<| and the word M protein " >h<uld |e>iu r n:ite that 

 irroiip of >nh^tanees uhich consists e>-entially of comhination- of 

 M-amino aci.U an<l their derivati^ 



The conjugated protein- are divided into (/) nucleo-pr.,tein., (h) 



i:l\co-prntein-. v phospho-proteins, (// liemoLrlohin>. d i lecitho- 



protein-. The nucleo-proteins are compound- of one or more pro- 

 tein molecule- with a nucleic acid. The phofipho-proteina are 

 compound- of the protein molecule with some, as yet unidentified, 

 phosphorus-containing .-uh-tance other than a nucleic acid or 

 lecithin. The lecitho-proteins are compounds of the protein molecule 

 with lecithins (lecithans, phosphat ids). 



J. PhvMol . l!Mir, 

 17 : 



Bioi, Chcin., I'.MMi. : 203. 

 rf Physiologic and Pathologic <'h-inistry. iM ed., 1902. 



