34 DEPARTMENT OF AClRICULTURE 



smear from this swelling. Disappearance slow and gradual the skin remaining hard 

 for several weeks. 



No. S. — Appeared February 11, 1907. Size about four centimetres in diameter. The 

 outer border was harder than the centre. February 13, swelling decreased. February 

 14. the fourth day, the swelling was harder and flatter. On the IGth the sixth day, only 

 a circular area of hardened skin remained. The swelling was punctured on February 

 11 and 14, there was no exudation of sanguineous fluid, but just sufficient blood for 

 three small smears on each date, all of which were negative. 



No. Jf. — Appeared on the same date as No. 3 and was slightly larger circular shaped 

 not (Edematous, situated just below point of left hip, very much diminished on Feb- 

 ruary 16. Skin remained hard for three weeks. Blood smears taken February 11 

 and 12, negative. 



Nos. 5 and 6. — Appeared August 25,1907, in the form of a double plaque over the 

 middle of the right ribs. The swellings adjoined one another, each being five to six 

 centimetres in diameter and raised one-half to one centimetre above the surface of the 

 surrounding skin. The swellings were quite firm, flat and not more raised at the centre 

 than at their circumference. Six microscopic preparations of the sero-sanguineous 

 contents were obtained from a puncture. Trypanosomata were found in two of these 

 si.\ specimens, the parasites being very few, vacuoled, swollen degenerated or in- 

 volution forms. 



The plaques had entirely disappeared on the third day after eruption. 



Ko. 7 — Appeared September 2, over the middle left ribs and was about the size 

 oj a silver dollar. Parasites could not be found in the fluid from puncture. 



September 4 only a trace of plaque No. 7 remained. 



September 7. Eeappearance of the plaque in the same position and of four smear 

 preparations made, Trypanosomata were found in one. The parasites were very rare. 



November 15. No further cutaneous lesions have appeared to date. 



None of these swellings could by any means be called a typical plaque, being 

 neither the distinctly (edematous, nor the disc shaped tumour as described by Lingard 

 and others. It is possible, however, that they appeared before the dates given above, 

 and were not observed until in the disappearing stage, which would account for the ab- 

 sence of the trypanosomata from the blood smears. 



One peculiar characteristic of the swellings is in the persistence of a hardened 

 area of skin for a very considerable time after the swelling has been absorbed. 



NERVOUS SYMPTOMS. 



On December 19th, 1906, there was a great tenderness and weakness of the loins. 

 The animal could be forced to the ground by slight pressure on the lumbo-sacral 

 nerves, on either side. 



Paraplegic symtoms of the hind limbs were pronounced. The hind-quarters 

 appeared 'dropped' and the loss of control was most evident. Both fore and hind 

 limbs were plac-ed in most erratic and singular positions. The attitude was crouching 

 The hind-quarters swung to the left, often remaining in that position when the animal 

 was at rest. Knuckling of the hind-fetlocks was extreme, the pasterns being at 

 times in contact with the ground. On being turned loose in the corral, locomotion 

 seemed almost entirely mechanical, the animal appearing to wish to travel in a 

 different direction to that w^hich her limbs were taking her. 



On December 29th, 1906, the animal was profusely bled from the jugular vein 

 until there were evinceci signs of distress and weakness. During the next week loco- 

 motion and the condition of the loins and limbs steadily improved. The knuckling 



