DOURINE OR MALADIE DU COIT 57 



willingly invited us to examine them at certain places where they were collected. 

 Four mares were declared dourdne suspects. The symptoms which they presented 

 were vague enough, but the stallion which had served them presented such evident 

 signs of dourine that less could not be done than to put them under the supervision 

 of the sanitary service. Blood taken from^ the tip of the ear and from the vagina of 

 two of these mares showed, aften long and minute examination some very sparse 

 trypanosomes. A dog and a rabbit received respectively the first 50 c.c, the second 

 20 cc, of blood from the jugular of another of these suspected mares. The rabbit 

 died some days afterwards from septicaemia. On the dog, which was carefully 

 watched every day, thene appeared on the seventh day, at the point of inoculation, 

 a swelling about the size of a hazel nut in the sero-sanguineous fluid of which we found 

 trypanosomes in sufficient numbers, which we submitted to the confirmatory examina- 

 tion of Messrs. Leclainche and Laveran. To this swelling, supervening at the point 

 of inoculation, the symptoms of dourine in the dog were confined. 



Let us add that three of the mares declared suspected by the sanitary commission 

 died after having presented the typical symptoms of dourine. A private stallion 

 was also castrated for dourine in the same district as that in which the affected mares 

 lived. We desire above all to deduct from this enzootic, interesting on more than 

 one account, the difficulty of bacteriological diagnosis and the positive discovery of 

 the Trypanosoma Bougeti in the dourine of France. 



In Hungary, aften having failed for a long time in his search for the trypano- 

 some. Prof. Marek has finally found it in the blood of a stallion affected with dourine 

 and has willingly announced to the International Congress of Veterinary Medicine 

 at Buda Pesth, that he would withdraw the reservations which he had expressed on 

 the subject of a specific trypanosome in Hungarian dourine. 



We will not close this note without tendering ouri hearty thanks to Prof. 

 Leclainche for the great obligation he has rendered us in facilitating our researches 

 and in permitting us to demonstrate the Single nature of dourine. 



