518 



placed Ler at hard work. "Want of feed and overwork and exposure 

 rapidly developed a ease of acute glanders, from which the animal 

 died, and at the autopsy were found the lesions of an acute pneumonia 

 of glanders grafted on chronic lesions, consisting of old tubercles, \^hich 

 had undoubtedly existed for years. 



In a recent case under the care of the writer a coach horse was ex- 

 amined for soundness and passed as sound by a prominent veterinarian, 

 who a few montlis afterwards treated the horse for a skin eruption 

 from which it recovered. Twelve months afterwards it came into the 

 hands of the writer, hidebound, with a slight cough and a slight 

 eruption of the skin, which was attiibuted to clipping and the rubbing 

 of the harness, but which had nothing suspicious in its character. The 

 horse was placed on tonics and put to regular light driving. In six 

 weeks it developed a bronchitis without having been specially exposed, 

 and in two days this trouble was followed by a lobular imeunionia and 

 the breaking of an abscess in the right lung. Farcy buds developed 

 on the surface of the body and the animal died. The autopsy- showed 

 the existence of a number of old tubercles in the lungs which must 

 have existed previous to purchase, more than a year before. 



Public watering troughs and the feed boxes of boarding stables and 

 the tavern stables of market towns are among the most common recip- 

 ients forthevirus of glanders, which is most dangerous in its fresh state, 

 but cases have been known to be caused by feeding animals in the box 

 or stall in which glanJered animals had stood more than a year before. 

 While the discharge from a case of chronic glanders is much less apt 

 to contain the virus than that from a case of acute glanders, the former, 

 if it infects an animal, will produce the same disease as the latter. It 

 may assume from the outset an acute or chronic form according to the 

 susceptibility of the animal infected, and this does not depend upon the 

 character of the disease from which the virus was derived. 



The genus equus, the horse, the ass, and the mule, are the animals 

 which are the most susceptible to contract glanders, but in these we 

 find a much greater receptivity in the ass and mule than we do in the 

 horse. In the ass and mule in almost all cases the period of incubation 

 is short and the disease develops in an acute form. We find that the 

 race of horse infected influences the character of the disease; in full- 

 blooded, fat horses, of a sanguinary temperament, the disease usually 

 develops in an acute form, while in the lymphatic, cold-blooded, more 

 common race of horses, the disease usually assumes a chronic form. If 

 the disease develops first in the chronic ffJVm in a horse in fair condition, 

 starvation and overwork are apt to bring on an acute attack, but when 

 the disease is inoculated into a debilitated and impoverished animal it 

 is apt to start in the latent form. Inoculation on the lips or the ex- 

 terior of the animal is frequently followed by an acute attack, while in- 

 fection by ingestion of the virus and inoculation by means of the diges- 

 tive tract is often followed by the trouble in the chronic latent form. 



