519 



In the dog the inoculation of glanders may develop a constitutioual 

 disease with all the symptoms which are found in the horse, but more 

 frequently the virus pullulates ouly at the point of inoculation, remain- 

 ing for some time as a local sore, which may then heal, leaving a per- 

 fectly sound animal ; but while the local sore is continuiug to ulcerate, 

 and specific virus exists in it, it may be the carrier of contagion to other 

 animals. In man we find a greater receptivity to glanders than in the 

 dog, and in many unfortunate cases the virus spreads from the point 

 of moculation to the entire system and destroys the wretched mortal 

 by extensive ulcers of the face and hemorrhage, or by destruction of 

 the luug tissue; in other cases, however, most fortunately, glanders 

 may develop as in the dog, only in local form, not infecting the consti- 

 tution and terminating in recovery, while the specific ulcer by proper 

 treatment is turned into a simple one. In the feline species glanders 

 is more destructive than in the dog. The point of inoculation ulcerates 

 rapidly and the entire system becomes infected. 



While a. student the writer saw a lion in the service of Prolessor 

 Trasbot, at ^fort, which had contracted the disease by eating glaudeied 

 meat and died with the lung farcied with tubercles. A litter of kittens 

 lapped at the blood from the lungs of a glandered horse on which an 

 autopsy was being made, and in ftmr days almost their entire faces, in- 

 cluding the nasal bones, were eaten away by rapid ulceration. Tuber- 

 cles were found in the lungs. 



A pack of wolves in the Philadelphia Zoological Garden died in ten 

 days alter being fed with the meat of a glandered horse. The rabbit, 

 Guinea pig, and mice are specially susceptible to the inoculation of 

 glanders, and the recent discoveries in regard to this disease have made 

 these animals most convenient witnesses and proofs of the existence of 

 suspected cases of the glanders in other animals by the results of suc- 

 cessful inoculations. 



The sheep and the goat are both capable of developing the disease. 

 The goat is more suscei)tible and frequently develops it by means of 

 the digestive tract, from its habit of eating droppings, rags, etc., which 

 are found in the neighborhood of the .stall. The pig is considered not 

 to be susceptible to glanders, and a large number of inoculations, to- 

 gether with the feeding of glandered meat to a pen of pigs at the vet- 

 erinary school at Alfort, failed to give these animals the disease, but 

 Bollinger reports that GerlacU has seen glanders in the i)ig nine months 

 after inoculation. An experiment of Spmola has also produced positive 

 results, so that we should consider it dangerous to allow a pig the use 

 of glandered meat. 



Horned cattle and barnyard fowls are absolutely exemi)t from attacks 

 of glanders, whether the virus is given to them by the digestive tract 

 or inoculated into their tissues. 



The previous reference to the existence of glanders under the two 

 forms more commonly difierentiated as glanders and as farcy, and our 



