524 



tbe pulse becomes quickened, and the temperature becomes elevated to 

 103°, 1040, or 105° F. 



With tbe otlier symptoms of an acute fever tlie general appearance 

 and station of the animal is that of one suffering from an acute imeu 

 monia, but upon examination, while we may find sibilant and mucous 

 rales over the side of the chest, and may possibly hear tubular murmurs 

 at the base of the neck over the trachea, we fail to find the tubular 

 murmur or the large area of dullness on percussion over the sides of the 

 chest which belongs to simple imeumonia. 



The posf-mortem examination of the lungs shows that the pneumonia 

 of glanders is a lobular, V-shaped pneumonia scattered through the 

 lungs and caused by the specific inflammatory process taking place at 

 tbe divergence of the smaller air tubes of the lungs. In some cases of 

 acute glanders the formation of tubercles may so irritate the mucous 

 membrane of tbe respiratory tract and cause such a profuse discharge 

 of muro-purulent, or purulent matter that the specific character of tbe 

 original discharge is entirely masked. In this case, too, the submaxil- 

 lary space may for a few days so swell as to resemble the oedematous 

 inflamed glands of strangles, equine variola, or laryngitis. This condi- 

 tion is especially apt to be marked in an acute outbreak of glanders in 

 a drove of mules. 



Cases of chronic farcy and glanders, if not destroyed, may live in a 

 depraved condition uutil the animal dies from general emaciation and 

 anaemia, but in the majority of cases, from some sudden exposure to 

 cold, it develops an acute pneumonia or other simple inflammatory 

 trouble which starts up the latent disease and the animal bas acute 

 glanders. 



In tbe ass, mule, and plethoric horses, acute glanders usually termi- 

 nates by lobular pneumonia. In other cases the general symptoms 

 may subside. The symptoms of pneumonia gradually disappear, tbe 

 temperature lowers, the pulse becomes slower, the ulcers heal, leaving 

 small indurated cicatrices, and the animal may return to apparent 

 health, or may at least be able to do a small amount of work with but 

 a few symptoms of the disease remaining in a chronic form. During 

 the attack of acute glanders the inflammation of tbe nasal cavities fre- 

 quently spreads into tbe sinuses or air cells, which are found in tbe 

 forehead and in front of tbe eyes on either side of tbe face, and cause 

 abscesses of these cavities, which may remain as tbe only visible symp- 

 tom of the disease. An animal which has recovered from a case of 

 acute glanders, like the animals which are affected by chronic glanders 

 and chronic farcy, are apt to be affected with emphysema of tbe lungs 

 or the heaves, and to have a chronic cough. In this condition they 

 may continue for a long period, serving as dangerous sources of conta- 

 gion, tbe mofe so because the slight amount of discharge does not 

 serve as a warning to the owner or driver as profuse discharge does in 

 the more acute cases. 



