182 MODERN BIOLOGIC THERAPEUSIS 



variolae vaccinae (cowpox)." News of the 

 discovery of vaccination spread rapidly to 

 America, but the difficulty of conveying the Vac- 

 cine Virus without loss of potency delayed the 

 first successful vaccination in the United States 

 until July 8, 1800, when Dr. Benjamin Water- 

 house, Professor of Medicine in Harvard Col- 

 lege, successfully vaccinated his son a boy 

 about five years of age. 



Preparation of Virus By the law of July 1, 

 1902, Vaccine Virus sold in interstate traffic in 

 the United States must come from a licensed 

 manufacturer. These licenses are issued by the 

 Secretary of the Treasury only after a careful 

 inspection of the plant, personnel, and product 

 by a competent government officer. In accord- 

 ance with an additional regulation issued by the 

 Secretary of the Treasury March 13, 1906, 

 each lot of Vaccine Virus must be examined 

 fully by modern bacteriologic methods to de- 

 termine the absence of pathogenic microorgan- 

 isms. 



Tests The following tests are made in our 

 laboratories on all Vaccine Virus in order to 

 insure its safety and activity: (1) Green virus 

 as harvested before "aging" is subjected to 



