VACCINES IN PROPHYLAXIS OF DISEASE 237 



The 21 cases reported by Manning were patients 

 who were already suffering from the disease, 

 and 14 of them were relieved objectively and 

 subjectively. Of the cases treated by Oppen- 

 lieimer and Gottlieb, 5 were treated during the 

 attack; and of these, 4 were promptly cured, 

 while the other patient received no benefit. 



If the vaccine is administered during the at- 

 tack of hay fever, it is important that the doses 

 be sufficiently spaced to prevent a severe reac- 

 tion. For this reason, most workers have 

 adopted intervals of 3 to 10 days. 



How to Secure Treatment Pollen Vaccine as 

 prepared in our laboratories has been demon- 

 strated to retain its potency unimpaired for a 

 period which is longer than the time necessary 

 to administer the complete prophylactic treat- 

 ment. The period of potency is stamped on 

 each package. The vaccine for each case to be 

 treated should be obtained by direct shipment 

 from the laboratories at the time when the phy- 

 sician desires to begin the treatment; and the 

 treatment should be started promptly in order 

 to be completed before the expiration date 

 stamped on the package. 



