Chapter XXI 



CUTANEOUS DISEASES 



Since Wright first applied the principles of 

 vaccine therapy to furunculosis and sycosis, 

 vaccines have been used in a number of other 

 cutaneous disorders with varying results. Vac- 

 cine therapy has its indications and is of un- 

 questionable value in certain conditions when 

 administered properly. Its value and beneficial 

 results are most noticeable in chronic or recur- 

 rent types of staphylococcic infections, such as 

 acne, furunculosis, sycosis vulgaris, etc. In cer- 

 tain types of acne vulgaris, Acne Vaccine has 

 proved its- value ; yet in these conditions vac- 

 cine therapy frequently fails to produce bene- 

 ficial results and is due in all probability, as 

 Wright believes, to the failure of the immuniz- 

 ing mechanism of the patient to produce anti- 

 bodies. In the vaccine treatment of cutaneous 

 disorders certain important factors must be con- 

 sidered, such as the dosage, interval between in- 

 oculations, individual susceptibility, etc. It 

 may be formulated as a general rule and a rigid 



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