268 MODERN BIOLOGIC THERAPEUSIS 



crease in discharge has been noted after the use 

 of vaccines, and this procedure has been sug- 

 gested as a method of determining the cure of 

 such cases. Active immunization in gonorrhea 

 has also been suggested as a means of prevent- 

 ing complications, by increasing immunity and 

 thus anticipating the possible spread of the in- 

 fection from the primary focus. Other bacteria, 

 such as the staphylococcus and colon bacillus, 

 undoubtedly play a large part in the continu- 

 ance of the urethral discharge; as also do the 

 mechanical difficulties, such as strictures, which 

 develop as a result of prolonged inflammation. 



Vulvovaginitis Some observers believe that 

 the course of vulvovaginitis in children has been 

 shortened by the use of vaccines ; others that the 

 methods have been of no demonstrable value. 

 It would appear that, while treatment by vac- 

 cines has not been clearly shown to shorten the 

 period of treatment, they may be cautiously 

 used in combination with other approved local 

 procedures. 



Ophthalmia A limited number of cases of 

 ophthalmia treated by vaccines have been re- 

 ported, but the results do not appear better than 

 infections of other mucous membranes. The col- 



