282 MODERN BIOLOGIC THERAPEUSIS 

 WHOOPING-COUGH 



Probably no disease which affects the human 

 subject, and particularly children, has so con- 

 sistently baffled the efforts of physicians to suc- 

 cessfully treat it as has whooping-cough. The 

 entire gamut of the pharmacopeia has been run 

 in an effort to discover a drug which would pro- 

 duce some consistent results, but to no avail. 

 Not until it was demonstrated that a specific 

 microorganism caused the disease was there any 

 hope of solving the perplexing problem of 

 treating whooping-cough. Early in the course 

 of the disease, the Bordet bacillus is present in 

 large numbers ; but after the first week, it is as- 

 sociated with the influenza bacillus, the pneu- 

 mococcus and other bacteria, the presence of 

 which favor the development of broncho-pneu- 

 monia which so frequently causes a fatal termi- 

 nation of this widespread disease. 



Vaccine Therapy The most recent, effective 

 and rational method of treating whooping- 

 cough is by means of a combined vaccine. Dr. 

 E. Mather Sill of the New York Polyclinic Hos- 

 pital and Medical School (American Journal of 

 Diseases of Children, May 1913, and American 

 Medicine, June 1913) has used this method of 



