Chapter XXIV 



ACUTE GENERAL INFECTIONS 



TYPHOID FEVER 



The most complete analysis of the bacterial 

 therapy of typhoid fever has been made by Wat- 

 ters (Medical Record, 1913, LXXXIV, 518) who 

 has summarized the results obtained in the 

 treatment of 1,120 cases, of which 158 had been 

 treated by himself during the past six years. 

 The mortality was 4.7 per cent. He states that 

 during a similar period of observation in 100 

 patients with typhoid not receiving vaccines, 

 there was a mortality of 13 per cent. It appears 

 from Watters' series that (1) the mortality was 

 slightly lower among the patients treated by 

 vaccine than among those who did not receive 

 such treatment; (2) the duration of fever was. 

 about ten days less in the vaccine-treated cases ; 

 and (3) the percentage of relapses was dimin- 

 ished in the vaccine-treated cases. 



Mortality Lowered by Vaccines Callison 

 (Medical Record, June 24, 1911, page 1129) col- 

 lected 323 cases in which this disease was treat- 



289 



