OF ALCOHOL UPON DIGESTION. 



93 



be the cause of gastric stimulation. It will be remembered 

 that even vigorous mechanical stimulation or irritation ordi- 

 narily fails to yield more than a few grams of secretion* an 

 observation in decided contrast to the phenomena of gastric 

 flow during the presence of digestible materials in the 

 stomach. The following experiments throw light on the 

 question raised: 



XI. 25 v, 1897. Dog. Weight 23 kilos. The intestine was ligatured just 



beyond the pylorus. Another ligature was applied below the point 

 of entrance of the duct of Wirsung. 20 c. c. of 60 per cent alcohol 

 were injected into the lumen of the intestine between these liga- 

 tures, while 105 c. c. of 60 per cent alcohol were introduced into the 

 intestine beyond the second ligature. Then 



Introduced 200 c. c. water into stomach at 10.45 A. M. 

 Contents removed at 2.30 p. M. = 3J hrs. 



Volume of fluid recovered from stomach 260 c. c. = 130 per cent 

 of original volume. 



Analysis of stomach contents gave : 



Total acidity 0.241 per cent. 



FreeHCl 0.213 



Loosely combined HC1 . . 0.002 

 Salts 0.026 



XII. 28 v, 1897. Bitch. Weight 28 kilos. Intestine ligatured just be- 



yond the pylorus. Another ligature was applied below the point 

 of entrance of the duct of Wirsung. 125 c. c. of 60 per cent 

 alcohol were injected into the lumen of the intestine below the 

 second ligature,t then 



Introduced 200 c. c. water into stomach at 11 A. M. 

 Contents removed at 2.45 p. M. = 3$ hours. 



Volume of fluid recovered from stomach = 375 c. c. = 187.5 per 

 Cent of original volume. 



Analysis of stomach contents gave : 



Total acidity 0.333 per cent. 



FreeHCl 0.306 



Loosely combined HC1 . . 0.004 



Salts 0.023 



Total solids 0.30 



* Cf . Tiedemann and Gmelin, Die Verdauung nach Versuchen, 1831, p. 92 ; 

 Schiff : Lemons sur la physiologic de la digestion, ii, p. 244. 



t The return of alcoholic fluid into the stomach was thus absolutely 

 prevented. 



