ON PANCREATIC PROTEOLYSIS. 



211 



Experiment 27. Dog's bile. Alkaline extract of pig's pancreas. 



Per cent of Bile. Undigested Residue. Fibrin Digested. Relative Proteolytic Action. 



0.3913 gram 60.87 per cent 



6.0 

 10.0 



0.3593 

 0.3622 



64.07 

 63.78 



100.0 

 106.2 

 104.6 



Experiment 28. Dog's bile. Alkaline extract of ox pancreas. 



Per cent of Bile. Undigested Residue. Fibrin Digested. Relative Proteolytic Action. 



0.6374 gram 46.26 per cent 100.0 



20.0 0.6267 47.33 102.3 



Experiment 29. Sheep's bile. Alkaline extract of ox pancreas. 



Per cent of Bile. Undigested Residue. Fibrin Digested. Relative Proteolytic Action. 







0.26 

 0.60 

 2.60 

 6.00 

 10.00 



0.3936 gram 



0.3880 



0.4079 



0.4236 



0.4136 



0.4002 



60.66 per cent 



61.20 



69.21 



67.64 



58.66 



100.0 

 100.9 

 97.6 

 95.3 

 96.7 

 98.8 



Experiment 30. Sheep's bile. Alkaline extract of ox pancreas. 



Undigested Residue. Fibrin Digested. Relative Proteolytic Action. 



Per cent of Bile. 

 

 



0.25 



0.60 



1.00 



2.50 



6.00 



10.00 



16.00 



100.0 



99.3 



99.8 



99.3 



101.9 



105.1 



105.5 



109.6 



112.8 



On looking through these results and comparing them with 

 those of the preceding series, it is apparent that the addition 

 of bile to an alkaline pancreatic juice is liable to produce a 

 greater relative retardation of proteolysis than the addition of 

 the same amount to a neutral pancreatic fluid. An alkaline 

 pancreatic juice, however, containing even 40 per cent of bile 

 will digest as much proteid in a given time as the same 

 pancreatic fluid neutralized but without the addition of bile. 

 If the control mixtures of the two series are compared, it will 

 be observed that the alkaline fluids dissolve on an average about 

 10-15 per cent more proteid than the neutral fluids. This is 



