KYNURENIC ACID. 



239 



The results obtained in the preceding experiment are sum- 

 marized in the following table, which gives the daily averages 

 for various feeding periods. 



DOG E. SUMMARY. 

 (Giving daily averages for various feeding periods.) 



In view of the peculiar chemical and physiological behavior 

 of gelatin in contrast to the ordinary proteids, some experi- 

 ments were undertaken with this albuminoid (Dogs F, G, H). 

 Commercial gelatin, containing 13.8 per cent N, was fed, it 

 being eagerly eaten when mixed with water and the other 

 food stuffs as indicated. Occasionally 1 to 2 grams of Lie- 

 big's extract of beef were added to improve the flavor, while 

 a mixture of inorganic salts as recommended by J. Munk * 

 was daily given with the food. The following dog, F, which 

 had some time previously been used in a phlorhizin experiment, 

 had been fed very large quantities of casern on the days im- 

 mediately preceding the experiment. 



At the conclusion of the experiment on the dog H, the 

 animal was starved for eighteen days. Body-weight fell from 

 7.6 kilos to 6.0 kilos. During this period 1220 c. c. of urine, 

 containing 107 mgr. kynurenic acid, were eliminated. 



* J. Munk, Virchow's Arch. f. d. exper. Pathologic, cxxxii, p. 102. 



