304 A CHEMICO-PHYSIOLOGICAL STUDY OF 



mose injections, no far-reaching conclusions can be drawn 

 from the data at hand. 



(4) Ordinary doses of deuterogelatose (0.3 gram per kilo) 

 give rise to no marked lymphagogic action, large amounts 

 being required to produce characteristic effects. This corre- 

 sponds with the other observations made on the physiological 

 action of this substance. With heteroalbumose, lymphagogic 

 action is as strongly marked as the action on blood coagula- 

 tion and arterial pressure already noted. 



(5) Previous injection of hemipeptone or deuterogelatose 

 is entirely without influence on the lymphagogic action of 

 heteroalbumose ; the latter producing a marked increase in 

 the flow of lymph when injected a short time after the action 

 of the primary substances has ceased. 



Influence on the flow of urine, etc. In conformity with 

 previous observations, our results, shown in the following 

 table, lead to the conclusion that the albumoses, owing to 

 their marked influence in lowering blood-pressure, tend to 

 cause a complete cessation of the flow of urine. With hetero- 

 albumose, however, the results seemingly justify a somewhat 

 different conclusion. Thus, in three experiments (XXI, 

 XXIV, and XXIX), some hours after the animals had re- 

 ceived injections of substances which act as diuretics and 

 lymphagogues, an injection of heteroalbumose was given. 

 This resulted in a complete stoppage of the flow of urine ; 

 not a drop of urine was obtained within the half hour or 

 more after this injection, although the fall of arterial pressure 

 was comparatively slight and transitory. Hence, it follows 

 that heteroalbumose, unlike the other albumoses, must exert 

 some influence upon the action of the kidneys independent 

 of blood-pressure; possibly, a specific influence upon the 

 secretory activity of the epithelial cells. In any event hetero- 

 albumose may check the formation of urine even when 

 arterial pressure is not materially affected. On the other 



view they find that "peptone" is an active " cholagogue." Starling and 

 others, however, have questioned this conclusion. See Proceedings of Fourth 

 International Physiological Congress. Centralbl. f. PhysioL, 1898, xii. 



