338 



OBSERVATIONS ON THE NITROGENOUS 



was examined for kynurenic acid with negative results. On 

 the two days of largest sugar excretion, the urine contained 10.0 

 grams of dextrose and 3.92 grams of nitrogen. 



These experiments failed to demonstrate any production of 

 kynurenic acid in the cat. We have made additional unsuc- 

 cessful attempts to find kynurenic acid in the urine of the 

 same animal under conditions of fasting and during an 

 abundant diet of both meat and pancreas. There is therefore 

 no modification of our earlier conclusion to be suggested.* 



EXPERIMENT L 



Four cats were used in this experiment. The meat fed was chopped lean 

 beef; the thymus was a preparation (Armour's) of the desiccated glands, and 

 was fed mixed with meat. 



Experiments on uric acid excretion The negative results 



just recorded induced us to ascertain whether similar differen- 

 ces exist between the organism of the cat and the dog in 

 respect to other important products of metabolism. Our 

 attention has thereby been directed particularly to the excre- 

 tion of uric acid and allantoin. Regarding the occurrence of 

 uric acid in the urine of the cat few references are to be 

 found in physiological literature. It is reported to be absent 

 frequently from the urine of both cat and dog, having been 

 found regularly only during animal diet and starvation. Dur- 



* Cf. Mendel and Jackson, loc. cit., p. 27. 



t Faeces in the urine ; a few crystals of uric acid were separated. 



