CONTENTS 



PAGE 



Antitoxins ..-.,-. I 



HISTORICAL i 



PRESENT METHOD OF PRODUCING DIPHTHERIA ANTI- 

 TOXIN 2 



PRODUCTION OF DIPHTHERIA TOXIN 2 



IMMUNIZING THE ANIMALS 3 



COLLECTING THE SERUM 4 



TESTING THE STRENGTH OF THE SERUM 5 



EHRLICH'S THEORY FOR PRODUCTION 6 



TOXINS, TOXOIDS 6 



RECEPTORS Q 



WEIGERT'S OVERPRODUCTION THEORY 10 



EXPERIMENTAL EVIDENCE FOR EHRLICH'S THEORY 13 



ANTIGENS OR HAPTINS 16 



NATURE OF ANTITOXINS IN GENERAL 17 



TOXINS AND OTHER POISONOUS CELL DERIVATIVES IN 



GENERAL 19 



RELATIONS BETWEEN TOXIN AND ANTITOXIN .... 21 



" L " and " Lf " 23 



PARTIAL SATURATION METHOD OF STUDYING TOXINS 



- TOXONS, TOXOIDS 23 



EHRLICH'S " POISON SPECTRA" 24 



VIEWS OF ARRHENIUS, BORDET, AND OTHERS ... 28 



Agglutinins 30 



THE PHENOMENON 30 



PURPOSE OF AGGLUTINATION 33 



HISTORICAL 33 



PFAUNDI.ER'S REACTION (THREAD REACTION) . . 35 



v 



