BACTERIOLYSINS AND H^MOLYSINS 85 



antih&molysin has been formed. As we know that 

 the action of the haemolysin depends on the com- 

 bined action of two substances, the immune body 

 and the complement, the question arises to which 

 of these two the antihaemolysin is related. Is it 

 an anti-immune body or an anti-complement? A 

 study of this question shows that both these sub- 

 stances are apparently present. In the serum of the 

 rabbit treated with specific haemolysin, both an anti- 

 immune body and an anti-complement have been 

 found. For the details of the experiments of 

 Ehrlich and Morgenroth and of Besredka, which dem- 

 onstrated this, I must refer to the original articles. 

 The first-named authors were further able to show 

 that the action of the anti-complement depended 

 on a haptophore group which it possessed, enabling 

 it to combine with the haptophore group of the 

 complement, thus satisfying this and hindering its 

 combination with the complementophile group of 

 the immune body. 



Anti-complement. Since the complements are 

 constituents of normal serum, it should be possible 

 to produce anti-complements by injecting animals 

 merely with normal serum; and they can, in fact, 

 be so produced. If rabbits are treated by inject- 

 ing them several times with normal guinea pig 

 serum, a serum may be obtained from these rabbits 

 which contains anti-complements against the com- 

 plements of normal guinea-pig serum. A serum 



