l6o APPENDIX. 



syphilitic, and obtained a positive reaction in 204. 

 They also tested 157 surely non-syphilitic individuals 

 as controls, and found all but two negative. These 

 two gave a doubtful reaction. 



In a recent paper Wassermann has collected data 

 on about 3000 tests, as follows: There were 1010 

 tests on cases surely non-syphilitic (controls), and 

 not one of these gave a positive reaction. Of the 

 1982 surely syphilitic cases tested, those examined 

 at the time when they had manifest symptoms 

 reacted in about 90% of the cases. When the cases 

 tested were without manifest symptoms, so-called 

 " latent syphilitics," about 50% reacted. 



As a matter of interest it may be mentioned that 

 Blumenthal and Wile tested the urine of syphilitic 

 individuals, and found that this too would give the 

 reaction. 



Marie and Levaditi examined the cerebrospinal 

 fluid of 30 cases of general paresis. All but two of 

 the cases gave a positive reaction. When the serum 

 was tested in place of the cerebrospinal fluid, the 

 percentage of positive findings dropped to 59%. 



Michaelis examined 20 cases of general paresis 

 and obtained a positive reaction in 1 8 of them. 



Citron examined 43 tabetics and paretics, and ob- 

 tained a positive reaction in 34 cases (79%). He 

 also tested the serum of 108 persons surely infected 

 with syphilis, or suspected to be infected, and ob- 

 tained a positive reaction in 80 (74%). None of the 

 sera from 156 surely non-syphilitic individuals gave 

 a positive reaction. 



