118 SIMPLE HISTOLOGICAL ELEMENTS. 



(4) two or three to a dozen scattered,.globular, transparent nucleoli. 

 (Figs. 56, 57, and 58.) 



Tubercle-corpuscles are distinguished from those of pus, from 

 being smaller, less granular, and not having their nucleoli aggre- 

 gated. Acetic acid also slightly affects their nucleoli ; while it must 

 often be applied to the nucleoli of pus-corpuscles, to render them 

 visible. The peculiar nuclei of cancer are distinguished from those 

 of tubercle by being larger, regularly oval, or not un frequently 

 spherical, and from containing only one or two nucleoli. 



As seen under the microscope, typhous and scrofulous deposits 

 are not to be distinguished from tubercle. 



Chemical analysis of the solid matter of tubercle gives the follow- 

 ing result. (Preuss.) Scherer, however, finds that tubercle varies 

 much in composition in different cases. 



1. Matters soluble in hot alcohol. 

 Cholesterine ... . - 4.94 



2. Matters soluble in cold alcohol, but not in water. 

 Oleate of soda . 'V . V . -C". *... 13.50 



3. Matters soluble in dilute alcohol. 

 A peculiar substance ) 



Lactate and sulphate of soda \ \ . . 8.46 

 Chloride of sodium ) 



4. Matters soluble in water. 

 Caseine 1 } 



Sulphate and phosphate of soda j- : . . 7.90 

 Chloride of sodium ) 



5. Matters insoluble in cold water and alcohol. 

 Caseine 1 altered by heat } 



Phosphate and carbonate of lime I . 65.11 



Oxide of iron, magnesia, and sulphur ) 



99.91 



In cretaceous transformation of tubercles, the salts of lime espe- 

 cially become increased. The small amount of fat existing in tu- 

 bercle has already been alluded to (p. 78). In a gray, well-dried 

 tubercular mass, Lehmann found but 3.54 per cent, of fat. The 

 cholesterine should not be regarded as fat. 



2. The exudation-corpuscle (inflammation-corpuscle of Gluge) con- 

 sists of a group of ten to forty or more granules, held together by 

 a coagulated albuminous matter, soluble in acetic acid. These mul- 

 berry-like bodies are also called granule-cells and glomeruli. 



They measure from 2? \^ to ?fa of an inch in diameter. They 



' An albuminous compoundj but not caseine. (Lehmann^ 



