MALTA OR MEDITERRANEAN FEVER. 125 



to twenty-one days. At the autopsy the spleen is found 

 enlarged and contains the micrococcus. 



In man the micrococcus is found in the enlarged spleen in 

 great numbers. 



Agglutination. Recent cultures of Micrococcus melitensis 

 are agglutinated by the blood-serum of patients suffering 

 from Malta fever, and occasionally with some this reaction 

 is manifested a year after recovery. This agglutinating effect 

 has been obtained in a dilution as high as 1 in 1000. 



QUESTIONS. 



Give the several names of the Micrococcus pneumonise ; by whom and how 

 was it discovered ? 



Where is it found ? 



What is its morphology? 



How does it stain ? 



How does it behave with regard to oxygen ? 



Does it possess flagella ? 



Is it motile ? 



In what media and at what temperature does it grow? 



What is its thermal death-point ? 



How does it grow in bouillon, gelatin, agar, blood-serum? 



What protects animals from inoculations with virulent cultures? 



What animals are susceptible ? 



What are the effects of subcutaneous and intrathoracic injection of animals? 



What is the synonym of the pneumococcus ? 



Is it a coccus ? 



By whom was it discovered ? 



Where is it found ? 



Give its morphology. Its staining properties. Give its principal bio- 

 logical characters. How does it grow in bouillon, in gelatin, on agar, on 

 blood-serum, on potato? 



What animals are susceptible ? 



Describe the effects of subcutaneous or intrathoracic inoculations. 



How is it differentiated from the preceding germ ? 



Where is the Diplococcus intracellularis meningitidis found? 



By whom was it discovered ? 



Give its morphology, its staining properties, its principal biologic charac- 

 ters? 



How is lumbar puncture performed ? 



What animals are susceptible ? 



How, and where should the inoculation be performed? 



Who discovered the Micrococcus melitensis ? 



Where was it found ? 



State its morphology, staining, its biologic characters. 



What animals are susceptible ? 



In what dilution does the blood of cases of Malta fever agglutinate cult- 

 ures of this micrococcus? 



