280 MICROBES, FERMENTS, AND MOULDS. 



In this case, it must be assumed that the bacilli and 

 spores of anthrax had settled on Klein's clothes, had 

 spread to the table and floor of the second cabinet, 

 and had passed thence on to the guinea-pig's hair 

 at the moment of the experiment. 



Another operator, who inoculated a guinea-pig 

 with human tubercles, worked at the same table as 

 that on which Klein performed his experiments on 

 anthrax. Two of the guinea-pigs died with Bacillus 

 anthracis in the blood. Yet the pipettes in use had 

 always been repointed in the fire, and all the other 

 instruments had been thoroughly heated before the 

 inoculation. 



In another case, on the contrary, a guinea-pig 

 inoculated with an attenuated culture of Bacillus 

 anthracis, of which the effect could not be fatal, was 

 examined at the end of some weeks, and all its organs 

 were found to be affected by the bacilli of tuberculosis. 

 On consulting his notes, Klein found that on the same 

 day he had performed experiments on tubercular 

 matter in the same laboratory, but he had always 

 been careful to use different instruments. The same 

 phenomenon was produced in a rabbit which died, not 

 of anthrax, with which he was supposed to have been 

 inoculated, but of general tuberculosis. The inocu- 

 lating liquid had clearly been impure. 



It is probable that Biichner's experiments on the 

 bacillus of meat were vitiated by a similar error. 

 Buchner inoculated mice with this bacillus, and believed 



