58 APPENDIX. 



7. Neither the heat of the body, nor the strength of the circulation, are causes of the 

 bloods's fluidity, they are both results of one cause, viz. the vital energy of the vessels ; 

 both are co-ordinate, and both as well as the phenomena of coagulation itself, are de- 

 pendent on this one source. 



8. That coagulation occurs sooner in venous than in arterial blood, and that coagu- 

 lation of arterial blood is still longer delayed if it be prevented from leaving the arte* 

 lies. 



9. That coagulation takes place the sooner after the blood is removed from the vital 

 sphere of the s;, stem, the weaker the vital energy to which it was subjected whilst cir- 

 culating in the system. 



10. That the weaker the vital energy, and, consequently, the quicker the coagula- 

 tion, the more lax is the coagulum which is formed. 



11. That, on the same principle, coagulation is more slow, and the coagulum more 

 firm, according as the vital influence of the vessels is more energetic. 



12. That the quantity of globules modifies these results ; a large proportion also of 

 these globules indicates great energy, and vice versa. 



13. That as the central globules retain their coloured envelopes, during their circula- 

 tion in the blood-vessels, and lose them soon after removal beyond the sphere of the vi- 

 tal influence of these vessels, and as this is a part, and indeed the first part of the act of 

 coagulation, so we consider, that it is in consequence of the vitality emanating from the 

 interior of the vessels into the blood, that the coloured envelopes of the central globules 

 continue to surround them ; and, consequently, that the separation of the envelope 

 from the central globule is the result of the loss of the chief portion of that vitality 

 which proceeds from the containing blood vessels ; and, as this loss of vitality may be 

 reasonably supposed to be quickest where it has been originally the least, therefore the 

 seperatioii of the envelopes and the coagulation will be the quicker the weaker the vi- 

 tal energy, and vice versa ; and the coagulum will be the more lax. 



14. That the loss of the vitality, emanating from the vessels, and, consequently, the 

 loss of their envelopes, disposes the central globules to attract each other ; and that in 

 the exertion of this contraction they dispose themselves into reticulated fibres, which 

 entangle the colouring matter and a portion of the serum ; and thus the clot is formed. 



15. It would appear that the central globules continue to retain, in the fibres which 

 they form, in the act of coagulation, a small portion of the vital enmaation with which 

 they were endowed ; in as much as the fibrous part of the coagulum evinces phenome- 

 an approaching to those denominated irritable ; and that it is the loss of the chief part of 

 the vitality, and not the whole of it, which occasions the separation of the coloured enve- 

 lopes from the central globules. 



16. That the firmness of the coagulumancl the irritable phenomena e vinced by its 

 fibrous part are proportionate in degree to the vital energies with which the vessels are 

 endowed by the ganglial nerves distributed in them, and to the emanation which the 

 globules themselves derive from this source. 



17. That the vital emanation, proceeding from the ganglial nerves distributed in the 

 vessels, affecting the globules in this manner, and giving rise to these phenomena, has 

 been the cause of, and has countenanced, the hypothesis of the vitality of the blood 

 a vitality which does not originally belong to it, which it possesses in a diminished de- 

 gree, and which is an emanation from a different source, which source is efficient in the 

 formation of the blood itself, and bestows on it through the medium of the vessels con- 

 taining it, the chief properties which this fluid evinces in health and in disease. 



18. That when the vitality of the blood-vessels is greatly diminished, as in purpura 

 haemorrhagica, scurvy, and in other diseases, coagulation either does not at all take 

 place, or it takes place very quickly and the coagulum is weak, lax, and resembling 

 cruor. Under such circumstances, the envelopes separate rapidly from the central glo- 

 bules, because the vitality of the vessels is scarcely sufficient to continue them in con- 

 nexion, even when circulating through the vessels themselves ; coagulation takes place 

 quickly, because the motion impressed upon the globules by the vital energy of the 

 vessels, owing to the defect of this energy, is soon lost, and because the separation of 

 the envelopes from the globules takes place almost instantly ; and the coagulum which 

 is formed is weak, or it does not form at all, because the vitality of the globules is in- 

 sufficient to dispose to an energetic attraction, or even to any attraction between the 

 central globules. 



19. and lastly. Opposite phenomena result from the increased energy of the vital 

 functions of the ganglial nerves distributed to the blood-vessels. 



