28 ON THE NATURE AND ACTION OF THE 



1.27. Head is drawn towards legs in a twitching fashion. 

 Animal bites at the left leg. When it moves about, the left 

 leg drags somewhat. 



1.45. Has been very quiet and disinclined to move for some 

 time. 



1.55. About 1 c.c. more was injected into the right thigh. 



1.56. Both hind legs drag slightly. 



1.58. The animal is very unsteady and tottering on its legs. 



2.2. Both hind legs completely paralysed, and, when the 

 animal draws itself forward with its fore-paws, the hind legs 

 trail out behind it. There are twitchings of the fore part of 

 the body. 



2.17. Hind legs and loins quite paralysed. The posterior 

 part of the body lies flat on the ground, the abdomen being 

 flattened out upon it. Paralysis seems gradually extending to 

 the fore limbs. There is general twitching. It tries to crawl, 

 but cannot drag itself forward, though it can still move the 

 fore legs. Gnaws the bottom of the box in which it lies. 



2.20. Almost motionless. Eye is still sensitive. Fluid has 

 issued from the mouth. The animal can still move its head. 



2.23. Convulsive movements. 



2.24. Cornea insensible. Weak twitches of the trunk still 

 occasionally occur ; they seem to be of the nature of respiratory 

 movements. Heart beats strongly. 



In a minute or two afterwards the animal was opened. The 

 heart was irritable and contracted when touched. The ventricle 

 did not contract unless touched. The auricles were beating. 

 The lungs were (I think) slightly congested. Blood from the 

 large trunks in the thorax was collected in a vessel : it was of 

 a dark colour; on exposure to air it became bright red and 

 formed a firm coagulum. Peristaltic movements of the intestine 

 were observed. 



Experiment VII. 



February 11th. — About J c.c. of milky -looking cobra-poison 

 was injected into the right thigh of a guinea-pig of moderate 

 size at 2.20. It became restless immediately, and the hind 

 legs began to twitch backwards. Shortly afterwards it again 

 became quiet and sat quite still. 



