SECRETION. 



419 



the epithelial covering of the posterior lobe into nervous tissue and 

 from it into the third ventricle to mix with the cerebrospinal fluid. 

 Schnitzler and Ewald found iodothyrin in the pituitary colloid. P. T. 

 Herring finds that removal of the thyroid is followed by an increased 

 production of colloid by the pituitary. Masses of colloid lie among 

 the cells and fibers of the nervous portion of the posterior lobe. The 

 posterior lobe of the pituitary is an infundibular brain gland, emptying 

 a colloid secretion into the third ventricle. 



Shafer has shown that the pituitary has a body unaltered by 



Fig. 155#. A Case of Acromegaly. (CASELLI.) 



boiling which excites diuresis, the diuresis not being due to changes in 

 blood-pressure. The infundibular part of the pituitary has a marked 

 influence on the uterine contractions, according to Shafer, Bell and 

 Hick. The effect upon uterine contraction has also- been confirmed by 

 Ott and Scott. Paulesco has found that ablation of the nervous or 

 infundibular lobe is compatible with an indefinite survival of an animal 

 and is not followed by any apparent trouble. The removal of the 

 pituitary is followed by coma, slow pulse and respiration, lowered 

 temperature and death. He has shown that from a functional point 

 of view the cortical layer of the epithelial anterior lobe is most 

 important. These experiments have been confirmed by Bedford ami 

 Cu sh ing. 



