Thrombosis. 



133 



body, testicles, etc., or of laked or altered blood, it is possible to 

 bring about extensive coagulation witb fatal effect. Such experi- 

 mental findings warrant the assumption that the occurrence of 

 tiirombosis is, at times, in infections and diseases accompanied by 

 tissue destruction dependent upon the coagulative action of microbic 

 poisons or tissue products permitting the formation of fibrin fer- 

 ment by the disintegration of leucocytes. 



2. Slowing and cessation of the blood current : It has been 



Fig. 4. 

 Cardiac valvular thrombosis (right ventrical of heart of hog). 



shown by experiment that after double ligation of a vein or artery, 

 although the blood in the segment between the ligatures is entirely 

 stagnant, it may remain fluid for months (Baumgarten, Senftleben 

 and others). Nevertheless in situations where blood vessels are 

 expanded, particularly when the seat of pathological dilatations, and 

 when the flow of the blood is slackened, thrombi are particularly 

 likely to form, because these ectases favor the agglutination of 

 leucocytes and plaques from which arises the inception of the 

 thrombotic process (stagnation tiirombosis) . 



