200 



Retrogressive Processes. 



hyaline (v. Reckling-hausen) , being characterized by its resistance 

 to acids, by being uninfluenced by water, alcohol or ether, and by 

 the fact that it is brilliantly stained with acid aniline dyes (eosin, 

 orange) and with carmine. 



This degeneration, or, as Diirk calls it, homogenization, occurs 

 according to Ribbert as a local metabolic disturbance, in which the 

 tissues do not properly use up the proteid supplied to them, do not 

 assimilate it all or throw it off before it is completely converted. 

 Such' substance is then precipitated all through the tissue overlying 

 the intercellular substance and destroying the latter and the cells 

 themselves (Ribbert). Hyaline formation is met principally in 



connective tissue and the vascular 

 apparatus, in h^emorrhagic and 

 anaemic infarcts, thrombi, false 

 membranes, in the areas of casea- 

 tion and in the connective tissue 

 of tuberculous lymph glands, in 

 neoplasms ; and to some extent the 

 substance occurs as a secretory 

 product, as the hyaline cylinders 

 of the uriniferous tubules. 



[A number of pathologists use 

 the term hyaline in a broad sense 

 to include the entire group of 

 changes productive of a homogen- 

 eous and luore or less glass-like 

 substance, as amyloid, colloid and 

 mucinous luaterial, as well as that 

 above referred to ; inasmuch, how- 

 ever, as these are capable of dif- 

 ferentiation from the substance in 

 hand, it seems well to consider 

 them separately. The relation of 

 hyaline degeneration to coagula- 

 tion necrosis as intimated by the 

 above description is clear, the hva- 

 line change suggesting from its ap- 

 pearances and results the so-called 

 fibrinoid product referred to in the discussion of coagulation. Hva- 

 line substance is, however, not entirely uniform, and the result of 

 further study may be expected to further dift'erentiate it into a num- 



Fig. 29. 



Muscle of horse (hiPinoglnbinfPniia 

 ten days after attaok) : a. nor 

 mal fibre; b. hvalino lump.=; 

 (After Zschokke.) 



