238 



Regeneration. 



tissue fibrils, the processes of the fibroblasts splitting up into fine 

 threads, at first in a brush like fashion, the protoplasm of the 

 cell gradually changing completely into a bundle of parallel fibrils 

 (Diirk, Neumann, Ziegler). Thus by the splitting of the enlarged 

 cell-body into fibrils the cell comes to resume the type of the fixed 

 connective tissue corpuscles, and the mass of proliferated fibroplastic 

 tissue assumes the character of adult connective tissue structure. 

 In addition to the fibrils the protoplasm of the connective tissue 

 cells gives ofif a greater or less amount of a soft mucoid inter- 

 cellular substance (Marchand). The young fibroblasts are con- 



^ 



■■H- 











** 











Fig. 43. 

 Fibroblasts and augiopla.sts in granulation tissue of licrse. 



tractile and consequently are inconstant in form ; they can project 

 processes of their substance and thus can surround other cells, 

 shreds of tissues and nutrient substances and incorporate them 

 like phagocytes. They can also change tlieir position^ this property 

 explaining the fact already mentioned that foci of disintegration, 

 areas of h senior rli,age and situations of other types of lesions are 

 penetrated and occupied, and foreign bodies are encapsulated by 

 these elements. Their motile power is so marked that if. for ex- 



