4o8 



Tumors. 



kiihn's crypts with of course considerable enlargement of the lumina, 

 and are characterized l)y marked production of mucin and by the 

 presence of numerous goblet cells among the lining epithelium. 

 Mammary cancers have so marked a tendency to *fat formation from 

 their cells arranged in alveoli, that milk-like fluid is usually found 

 filling the tubular cancerous spaces ; and ovarian cancers undergo 

 the formation of cysts which might well be mistaken for the 

 follicles. 





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Hard adenocarfiuoma of mammary gland of a Ijitcli ; shows the predominance of 

 the connective tissue stroma, the preservation of duct and acinous arrange- 

 ment of epithelium (as at a), but also the irregular and excessive epithelial 

 formation of solid cords and infiltration of tissues by their penetrating 

 anastomoses (as at b). 



The same structure, too, is repeated in the metastatic nodes in 

 the lungs, peritoneum and elsewhere, proving their derivation from 

 the primary tumor and its original source. 



This correspondence in cellular character between the carcinoma 

 and the gland from which it originated is, however, not always ap- 

 parent, the atypical nature of the growth manifesting itself in the 

 extension of the cells beyond their normal limiting membranes, 



