CIIK.MIC.M. I'.AMS ol Till: AM.MAL P,nlY. 



slight extent the non-nitro^enou- in.-t;il...li-in ..f tin- l....ly. ami thus 



re aide t. undergo a destructive metabolism .-.imilar to ti 

 tin- pn-teid-, cannot, "ii tin- other hand, play any part in th, 

 structhe nitni^eiioii> metaboli.-in which lead- to tin- format imi ..f pr <( - 

 In other word- tin- nitr-'^'-n contained in gelatin cannot In- 

 built up into the nitn . i.i-oteid. 1 \\ V .|.. not 

 any information which enable- u- to formulate an\ n-a-on for this 

 il behaviour of gelatin. It ha- l>-rn .1 that tin- al 



-:diie- in gelatin (- al\i-) nii^lit a.-.-oiint for tin- pln- 

 iioni.-non.- luit experiment- in \\hich animaU ha\.- l..-.-!i f.-.l \\ith 

 :n have not continued thi> vi-\v. 8 It aj.pear- that a 

 coii-idt-raldr ainou 1 'in i- ili'4--ti-d and al>-oi-hrd in iian. 



.ippi-ars in tic .ind nn-at (iiiu>i-h-) may contain a> niurli 



.itin: furthi-i. \|..-riiii.-nt- >ho\v that a do^' may 



; tin- ^'l.itin adniini-ti-rcd in tin- form of 



11^' tln-- fart> in mind and kiio\\in^ that p-latin u\>- 



pear to !>< ni"i- nadil\ im-taii<di>cil than proti-id.-. \\f may regard 



t a \alualdi- f l->tuff. hut not a- a f 1 \\hirh can supply 



tin- nitro^eiiini> m 'In- ti--m-- tliem-eh e-. The fai-t- thus 



: max >iipply an e\].lanat imi <!" the heiielicial effi-.-t- \\hi<-h art- 

 >upp.-ed t.. re-ult from tlie UM- of jellie> in training diets. 6 



Chondrin. 



Tli- matrix >f liyalim- cartilage is composed of an -la-ti'-. -emi- 

 xnvnt sul. -tancr which i< insululili- in cold <r hot water and 

 11 up aj.pivcial.lv liy t ivat iin-nt with i-itln-r water or 

 tlilut' at id. I'.y jirulmiL'f'l treatment with water umlt-r 



:re in a l ( a].iir< .li-j-ster it 18 gradually dissolved and yields 

 iition wlii li gelatinises mi runliuo and now contains th- 

 nice usually -jMikfii of as chondrin. The hyaline mat; 

 .age appear^ tints to hear tin- same relationshij' to chondrin 

 that the groand-sabatanoe of connective-tissue (collagen) d 



id 1- therefore frei|Ueilily Spoken of as 'cliolldl 



The -ul.-tanre known as chondrin. which is obtained in solution 

 by the action of -ii]-rheated water on hyaline cai t ilao'. exhibits 



icteri<tic n-actioii-.' It is precipitate,! 

 which does not. even if iii .-, Mi-id, -rabh- exec--. ivdi--,dve the 



te; minute quantities of minei similarly cause a 



< to apjM-ar which is in this case i .duble in the 



slightest excess of tin- acids. These reaction to distinguish 



n chondrin and -j'-latin. and a further di-tinction maybe 



on the basi-. of the fact tli.it -,]ut j, .n- ,,f chondrin are pre- 



i ted by several reagents such as alum, normal lead acetate, 



H.I. xin run), ft -.: ^. SOB. 



' II. rrti.inn II K- \\> ',rrh. ti. H" k, 1876, & 86. 



'/ / ,../. Miin. hen. 1885. 



il.. Kt/in 



* K' uiritioiial. mUlMi1ir anil ) 



gelatin w IlermaonV //<//Wi .///,,,. ..^. 1 5.1 M H .195. 



lewbott u. Ful.ini. MolewhoCt's t'nt,n*cA Bd. xi 104. 



