BASIS OF Tin: ANIMAL r,>i>\. 89 



ami dissolved, ami the urn-lei separated from them. A further 



purification i- obtained l.y treatment \\ith alcohol and ether ami 



final digestion with jx-jisiii in a-id solution, which does not 



the substance of the nuclei. 1 Tin- final residue thus obtained i- 



d with dilute acid, di--ol\ed in ak caustic soda, 



j'itated liy hydriH-hlouc acid. ami wa-hed with water and 



ali - iih"l. i by the above methods, nuclein jg ftp amorphous 



sulistanee,jjeh in phosphorus. which is set fire a- pho-j.i 



wJlen it js iKMtebTwitlTalkalis. At the same time some form of 



TiTusually makes Its appearance, aa also do the crystalline 



ances of the xanthin series, ^iinnin (?) and hyjM.xanthin. 



when the nuclein is ln-at-d with dilute mineral acids instead of 



alkalis. 1 It-appears, however, that the absolute and relative 



aim iimt of the above possible products of its deconnmsition varies 



with the source from which the nuclein is nhtflinml 



I'mlt-r tli- iiaim- 'adi-nin' K<>>,>cl lia- inri- n-ccntly ilf..-rilcd a m-\v 

 base which lie ..l.tained \>\ tli- di-c..inj...>it imi ! miclrin fniii \ra-t-r.-lU 

 with dilute >.ul]iluiric arid and heat. 1 It i> <Tv>talliin-, n-adily ->lulilr 

 in warm \vat-r and can-tic alkali-, and \\ln-n treated with nitrous acid 



IM.XHIitllin. (See lieloW.) 



il N,- r -H 2 0=C 4 H 4 X 4 0- r -NlI 1 . 



When egg- >r -eniin-alliuniin is precipitated with iiii'tuph<>.sphi>ric 

 i phoaphorised substance is obtained which exhibit- many ..f the 

 :-tic nf nuclein. 4 It di>e- imt, li"\ve\er. yield any 

 f tin- xanthin ha-e- when treated with acid-.'' 



Nucleo-albumins. 



While th.- nuclei may be regarded as coinixised j.rim -ij.all\ ..i 



the somewhat unsatisfactorily li.n nucli-ins. tin-re is evi- 



the existence 6 of closely allied <ul'-tam - t., which, -in.-.- 



'o be a compound of nuclein ami a pn-leid. the name 



nucleo-all.uniin has been Driven. < Mir kn- "f these -ul'- 



8 is as yet rudimentary and imjH-rl'ei t. and s U l.se<|Uent 



invest iu'ati'Mi mu-t d.-cid-- tln-ir real nature and their relat n-n-hip 



to tin- nucleins. 



The more characti-ri-tic reaetioux of the nucleo-alhumins m.iv 

 be- stated as foil lul.l.- in very dilute alkalis, the 



> It *bo fwbto the action of iry|*in Bokar, Xi.f f*iJ. Ckm. IU i . 



,,W. Cktm. Bd. r. (I- MII 



WM - 



./. rfrm C,wl\ 1885, So. 79. 1928. Xt ,.h*,i,J. <'/., 

 8. 8&0 S<hiiull MM (1889), H. 432. Brahtw, /&</. Bd. xiv. (1990), 



naim, tirr. d d rhrm. f, ftt H (|WM|. S S9 fflilKvr'i Arrk. 11.1 M MI 



/,yo/. Ckrm. Bd xm. (1889). S. 9S. 



\\ xm .I-T4.. S 194. 



