CHEMICAL BASIS OF Till-: ANIMAL BOD\ 

 established data, 1 while that in arterial blood is L'I-US mm.- It 



is furlher stated that lli.- stron-, T solutions nl' li.riuou'lobiii absorb 

 relatively LeSfl Carbon-dioxide than tin- weaker, aiul thai, as in the 

 case of oxy-hemqglohui (see p. L!L!l ) various modification-, i 

 ha-miiLjlubin i-xisi possessing dillerenl powers ,t' uniting with this 



< >n comparing the amounts of carbon-dioxide ami of 01 

 ..! ( '( > or N'( ) which may unite with a ^ivm weight of haemoglobin 

 it is at once evident that tin; mode of union t' the form- 

 must In- ditlerent from that of the latter three, with which, as 

 already stated, ha-moidobin unites molecule for molecule. This 

 difference in behaviour is very probably due to the decomposition 

 which lia-moolobin undergoes when a current of carbon-dioxide is 

 I through it, 3 and indeed it is hence probable that the so- 

 called carbon-dioxide h.emo^lobin i- rather a compound of the gas 

 with a coloured product of the decomposition of ha-mo^lobin, viz. 

 tuemochromogen, which has been shown by Hoppe-Seyler to unite 

 with carbon-monoxide (see below). The compound, whatever be 

 it- true nature, is stated to exhibit a one-banded absorption 

 trum closely similar to that of ha-mo^lobin, but the centre of the 

 band lies slightly more towards the violet end of the spectrum. 4 

 Piohr state- that tin- absorption of carbon-dioxide is independent 

 of the simultaneous presence of oxygen. 5 



Tin- ai-eiiratt- ipiantitat ivi- determination of the amount <>f h;em<>- 



k'l.'liin in any jjiven snlut KMI i- a matter <!' extn-iue imp..rt:iin-i-. n.it 



mi-rely in connection with several of the statemente oonteinad in the 



iini; il.--<-ript i..n <>(' (UBmoglohin and it- cniiipMiinds with gases, 

 l>nt al>.' in many in\ e>t i^at i.ms \\lii.-li turn .n tin- \aryin^ aiiimit* 

 .t" tin- >iil>-tanei- umler < 1 1 He re n t i-xpi-riim-ntal r< unlit i<m-. and lurtln-r 

 t'..r rlinii-al purposes. It may tln-n-t'..re n<>t l>e <>ut ! plan- t. il.-.<Tiln- 

 hrii-tly tin- prim-iples n \\lii.-li the ili-teriiiinat ins are l>a-.-.l. r.-l'.-rniiL: 

 tin- n-adi-r t>. sp.-cial \\.irk- fi.r the detail- "t tin- n->pi-i-t ive | 



The ini-thiiils eiiipl.-yi-d fall under tw.. <-ateg.'ries : chemical ami 



pll\ -i. :il. 



1. Chemical. ". Tin- ainmint ..f iron pre-ent in KM) par 

 ha-mogloKin has Keen frequently determined for thfl ''1 ..... 1 ..f \arimis 

 animals. It may !>> -tat.-. I t- !. al>"iit p.e. II. ne.- it" a 



siiliitmn of thi> lahttanoe be evaporated t.. drym--- and tin- ri->i<ln.' 



iiii-ini-rati-il, the ainmiiit >'t" lia'iiK.^l.'liin may In- inf.-rrrd I'r-.m the 



WulffLfru'. I'!! IM vi (is;.'i. S J.I. Straiwliurp, Ibid. \ 

 Nnwhnnin. ///. I 



- Hut <-f M.il.r, I'.nlr.ill. t /'/,,/>"/. H-l. i. (ISS7). S. -JM. n. (1888), S. 4.-I7. uh.i 

 makett it inii.-li l'->s. An ..nlint: t.. th tin- j.:irti;il pri-xxuro i>f ' 

 M<M1 in ICM than that of expiri'.l air. ami tl : -r.-at.T. If tlii> >li.-til.l 

 |in>\.- to ! tin- <-:ir> on further nn< ti^ati.ni. it u.nil.l apjK-ar that tho ffutoont 

 iiii.T. lianyo whirh taken plai-c in tin- IIIIIL'* < annut ! tin- pviilt if a jmn-ly .iiffunivo 



\v In-Ill to IM- ($ . 



-li|. See Abut. In M IIS 



* T.-nij.. /. "t. and see aLv. :<. KoalaMtaMbiBdamg dm Blutea," 

 KopcnhaL''-!!. 1887. 



tndmav. Arch.f. Phyriol. Bd. III. (1891), S. 62. 



