CONTENTS 



PAGE 



Antitoxins i 



HISTORICAL ; i 



PRESENT METHOD OF PRODUCING DIPHTHERIA ANTI- 

 TOXIN 2 



PRODUCTION OF DIPHTHERIA TOXIN 2 



IMMUNIZING THE ANIMALS 3 



COLLECTING THE SERUM 4 



TESTING THE STRENGTH OF THE SERUM 5 



EHRLICH'S THEORY FOR PRODUCTION 6 



TOXINS, TOXOIDS 6 



RECEPTORS 9 



WEIGERT'S OVERPRODUCTION THEORY 10 



EXPERIMENTAL EVIDENCE FOR EHRLICH'S THEORY... . 13 



ANTIGENS OR HAPTINS 16 



NATURE OF ANTITOXINS IN GENERAL 17 



TOXINS AND OTHER POISONOUS CELL DERIVATIVES IN 



GENERAL 20 



RELATIONS BETWEEN TOXIN AND ANTITOXIN 22 



"L "and "L t " 23 



PARTIAL SATURATION METHOD OF STUDYING TOXINS 



TOXONS, TOXOIDS 23 



EHRLICH'S " POISON SPECTRA " 24 



VIEWS OF ARRHENIUS, BORDET, AND OTHERS 28 



Agglutinins 3 2 



THE PHENOMENON 32 



H^MAGGLUTININS 34 



ISOAGGLUTININS 35 



PURPOSE OF AGGLUTINATION 36 



HISTORICAL 37 



PFAUNDLER'S REACTION (THREAD REACTION). . 38 



vii 



