88 IMMUNE SERA 



both these substances are apparently present. In 

 the serum of the rabbit treated with specific haemo- 

 lysin, both an anti-immune body and an anti- 

 complement have been found. Ehrlich and Mor- 

 genroth were further able to show that the action 

 of the anti-complement depended on a haptophore 

 group which it possessed, enabling it to combine 

 with the haptophore group of the complement, 

 thus satisfying this and hindering its combination 

 with the complementophile group of the immune 

 body. 



" Anti- complement." l *Since the complements are 

 constituents of normal serum, it should be possible 

 to produce anti-complements by injecting animals 

 merely with normal serum; and they can, in fact, 

 be so produced. If rabbits are treated by inject- 

 ing them several times with normal guinea pig 

 serum, a serum may be obtained from these rabbits 

 which contains anti-complements against the com- 

 plements of normal guinea-pig serum. A serum 

 obtained in this way of course contains only one of 

 the antihaemolytic bodies, the anticomplement, 

 and not the antiimmune body. This is because 

 normal serum is too poor in immune body (inter- 

 body) to excite the production of any antiimmune 

 body. 



1 The existence of anti-complements is denied by Bordet, 

 Gay and others. For a statement of their views see pa<je 

 96. 



