72 Mr. P, Kooievaar on the 



in the fat a green granular mass ; above it is flabby and 

 cedematou?!. 



"With a view to making sure whether these spinal Iarva3 

 were the larv^ of Hi/poderma, 1 inserted tliem under the skin 

 of another animal, in order that they might there become 

 adult and in order from them, if possible, to breed Hypo- 

 derma bovis. 



1 selccfed as subject of ('XjU'rinient a small dog, which 

 sir;ce the beginnino- of January had been supplied with food 

 initctcd with Echinococcns vefennoriim. On February 8rd 



1 introduced, under ase])tic ])recautions, through an opening 



2 ceutinicties wide, beneath tlie skin in the left lumbir region 

 eleven s| in;i] CEf-trvs-larviv taken from a calf. The wound 

 was closed and h< aled quiikly, the state of the dog remained 

 normal, and nothing was seen of the eleven larvte inserted. 



Eight days later in the same munner fifteen larvai were 

 introduced under the skin of the right side ; scarct-ly an hour 

 later one of my colleagues and I reo|)cned the wound, and saw 

 to our astonishn ent that all the larvte with the exception of 

 one had disapj enred. Two days afterwards I observed a 

 larva lying under the skin on tlie costal wall, 8 centimetres 

 away from the wound ; its rounded oblong form was dis- 

 tinctly visible through the thin skin of the dog; one could 

 feel it roll under the finger. On the third day it had crawled 

 forward as far as the spinous processes,. and on the fourth it 

 had disappeared. 



The dog remained normal ; fourteen days after the first 

 insertion there was still nothing to be seen under the skin. 

 What had become of the twenty-six larvae in the dog? 

 To settle the point 1 decided to open the animal. 

 The autopsy was interesting. 



On removing the skin five still living larvfe were found in 

 the subcutis — one on the left costal wall, one in front of the 

 shoulder, one on the right thigh, one on the skull, and the 

 fifth larva on the point of the jaw. In the subcutis and in 

 the underlying muscles no traces of their wanderings were 

 observable; but certain cedematous spots were found in the 

 subcutis and the muscles. 



On opening the abdomen some bloody matter exuded. 

 Six larvae were found between the folds of the intestine, and 

 therefore free in the peritoneal cavity. 



I found, further, five larvse in the fat of the spleen, kidneys, 

 omentum, inguinal canal, and the retro-peritoneal tissue; the 

 removal of the kidneys disclosed three more larvje upon the 

 psoas muscles. 



In the pleural cavities no larva3 were found lying free; still 

 five larvffi weie met with, three of which were in the wall of 

 the cesophagus and two in the peritracheal tissue. 



