HILARY KOPRPOWSKI 
5. Do not overvaccinate for protection against diseases. 
Employ only vaccines which, while protecting against one 
pathogen, do not spread another. Preferably, use vaccine 
types which will maintain the balance between infectious 
agents and their human host, replacing the more virulent 
pathogen by a more attenuated one. 
6. Do not engage in programmes of eradication of infec- 
tious diseases. You will only drive the causative agents 
underground where they will become engaged in never- 
ending guerrilla warfare. 
7. Ifa universal antibiotic is found, immediately organize 
societies to prevent its use. It should be dealt with as we 
should have treated, and did not treat, the atomic bomb. Use 
any feasible national and international deterrents to prevent 
it falling into the hands of stupid people who probably will 
still be in the majority in your time as they were in mine. 
8. Have fun. You probably guessed from my own 
experience that you will never leave this world alive. 
Discussions which were held with Dr. Robert Austrian, University 
of Pennsylvania, Dr. René Dubos, of the Rockefeller Institute, and 
Dr. Eberhard Wecker, of the Wistar Institute, greatly helped in 
formulating the ideas incorporated in this paper; the author thanks 
them. 
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