Notefi on certain Blood- Tnhnlntinq Protozoa. 243 



radiations can be seen to pass out from it. I am not yet 

 clear as to the origin of this structure (Figs. 17, 21). As to 

 its position — it usually lies in close contact with the eosino- 

 phile body. This is an interesting point of resemblance to 

 the already cited Herpetomonas of kala-azar, where the 

 blepharoplast and eosinophile body are in the same close 

 topographical relation to one another. Occasionally the 

 centrosome lies behind the eosinophile body near to the 

 nucleus. In one case it appeared to be inside the eosinophile 

 body (Fig. 21). The size and appearance of the parasite 

 shows considerable variation. The usual form (Figs. 13, 14, 

 16, 17) is rather slim, with very finely alveolar protoplasm, 

 and few, if any granules, but forms are to be met with which 

 are of markedly larger dimensions, both broader and longer, 

 and with a more granular protoplasm. The alveolar structure 

 of the protoplasm is often exquisitely clear in these latter 

 forms (Figs. 18 to 22). The nucleus of this form is very 

 large, and has a more scattered irregular appearance: the 

 eosinophile body is occasionally missing. This is very 

 possibly a macrogamete. Forms intermediate as to size are 

 found between these and the ordinary individual. I take 

 them to be probably young female forms; they are dis- 

 tinguished by the abnormal size of the nucleus, which may 

 occupy two-thirds of the whole animal. The characteristic 

 configuration of the chromatin is not to be made out in these 

 specimens, the whole nucleus having a deeply staining, 

 almost reticulate appearance. Large forms with two nuclei 

 are found, and of these, two types, as far as I can see at 

 present, are to be distinguished: (1) those where (Fig. 22) 

 the two nuclei show the ordinary number of chromosomes; 

 and (2) those which show (Fig. 23) only four chromatin 

 masses. This last suggests a reduction division, but I have 

 not got sufficient information to make a definite statement, 

 more especially as this is a point which requires very careful 

 investigation in forms such as the one at present under 

 discussion. 



The details of division are still very obscure, owing to lack 

 of material, but there appears to be, as in many trypanosomes 

 (and other Protozoa, e.g., Euglena and Coccidium schitbergi), a 



