466 Proceedings of the Royal Physical Society. 



affected, especially in the immediate neighbourhood of the 

 puncture. ... In the central mass of the tumour, this 

 grey infiltration is most marked, but the altered muscle 

 has still preserved its fasciculated appearance, and it is easy 

 to see with the naked eye, in sections parallel to the long 

 axis of the fasciculi, bands more opaque and yellower, separat- 

 ing the grey fasciculi. The opaque bands resulting from an 

 inflammation of the connective tissue situated between the 

 secondary muscle fasciculi, and the grey fasciculi are neither 

 more nor less than muscular bundles. The lesion is least 

 marked at the periphery of the tumour, so that the grey and 

 opaque bands are irregularly separated by pink or white and 

 semi-transparent muscular fibres. 



" One sees, in fact, at the periphery, congestion, and a dis- 

 tension of the vessels with blood, which is not present at the 

 centre of the tumour." ..." Sections made of a piece 

 of this tissue hardened in alcohol, and examined unstained, 

 present a very characteristic transverse 'fragmentation' of 

 the muscles. Each of the small fragments appears homo- 

 geneous, glistening, transparent; it represents a transverse 

 disc, comprising the whole thickness of the primitive 

 fasciculus; and all these fasciculi are divided into a large 

 number of broken fragments separated by obscure interstices, 

 in which one sees the irregular margins of contiguous 

 fragments. These fragments are not usually thicker than 

 the primitive fasciculus that they replace, though it is not 

 rare to find some which are thick, of a greater diameter than 

 that of the primitive fasciculus, and at the two extremities 

 of which one observes an infolding of the sarcolemma which 

 contains them." 



Cornil then compares what he describes with Zenker's 

 vitreous degeneration, but points out that in Fowl Cholera 

 there is no extraversation of blood in the altered parts 

 similar to that observed sometimes in Typhoid Fever, and 

 accounts for this by the fact that in consequence of the 

 inflammation of the connective tissue between the primary 

 and secondary muscular fasciculi there is obliteration of the 

 vessels and arrest of the circulation. In the specimen 

 described above, there were seen, on staining with picro- 



