Caseous Tumours found in the 3fuscles of the Hake. 467 



carmine the primitive muscular fasciculi "divided trans- 

 versely into a multitude of small fragments. The large bands 

 less coloured" (than the muscular fibres) "represent the 

 connective tissue which separates the secondary bundles, and 

 are occupied by lymph cells and micro-organisms situated in 

 the middle of a reticulum of fibrin." 



" The fragments of muscle still possess at intervals their 

 transverse striation. The fragmentation is due to the 

 entrance of micro-organisms into the sacrolemma and to 

 atrophy; to consequent disappearance at intervals of the 

 muscular substance." . . . "It is not rare to see in 

 longitudinal sections of these altered muscles, primitive 

 fasciculi completely replaced, for a certain extent, by lymph 

 cells and microbes, which thus resemble inflamed connec- 

 tive tissue." 



After describing the arrest of the circulation in the altered 

 muscle by distension of the capillary vessels with lymph 

 cells, microbes, and fibrin, Cornil gives a most accurate 

 description of the condition observed by me in the muscle 

 of the fish. 



" Following these lesions, the muscle altered, as if solidified, 

 becomes compact, lardaceous, opaque, is condemned in its 

 central portion to a local mortification, the circulation going 

 on no longer, its proper tissue being stuffed with a number 

 of organisms pressed one against the other, and are unable to 

 find material sufficient for their nutrition." ..." There 

 results a 'sequestrum,' a necrosed portion which has been 

 well described to the naked eye by Pasteur, which is isolated 

 from the neighbouring tissues in which the circulation has 

 still been kept up." 



He then goes on to point out the various stages through 

 which the different parts of the altered tissues pass, and 

 at the fourteenth or sixteenth day describes a space which 

 surrounds the sequestrum. This is partially fiUed with 

 droplets of fat, not adipose tissue. Some of these " adhere to 

 the margin, more or less regular, of the sequestrum, which is 

 formed of the vitreous muscular blocks, and by the dead 

 connective tissue. Other droplets are attached to the walls 

 of the living tissue." Within the cavity he describes a 



VOL. VIII. 2 G 



