NO. IO COCKROACHES—ROTH AND WILLIS 39 
Koehler (1878) prescribed Tarakanen for 13 patients with the 
following diseases: arteriosclerosis (I case), atherosis and angina 
pectoris (1), nephritis (4), exudative pleurisy (1), pernicious anemia 
(1), heart disease (1), exudative pericarditis (1), and Bright’s dis- 
ease (3). In all cases there was increased excretion of sweat and 
urine; edema and ascites were reduced or completely disappeared ; 
albumin was reduced (2 cases) or eliminated (5 cases) ; stomach and 
intestine were not irritated. 
Fronmuller (1878) used powdered Blatia orientalis as a diuretic 
in treating patients with lung tuberculosis (3 cases), bronchitis (1), 
exudative pleurisy (1), and albuminuria (1). Five of the six pa- 
tients showed increased urine output; there was no digestive dis- 
turbance; it was concluded that the stronger doses of Blatta were 
strikingly effective and were not bad to take. 
Budde (1878) used powdered Blatta to treat patients with al- 
buminuria (2 cases) and nephritis (3 cases). He was unable to con- 
clude that the therapy was effective. There was not a distinct increase 
in urine excretion or sweating, and the excretion of albumin remained 
unchanged. 
Wyschinski (1879) used Blatia in treating patients with dropsy 
(7 cases), cirrhosis of the liver (2), organic heart disease (4), and 
Bright’s disease (1). Excretion of urine increased in the patients with 
cirrhosis of the liver. The results with the other patients were nega- 
tive, and Wyschinski questioned whether antihydropin from Blatta 
had produced the effects claimed by Bogomolow and Unterberger. 
Kurz (1879) reported that he used Blatta in treating a man with 
nephritis and a girl with chronic peritonitis and ascites. The urine 
output increased in both patients ; the amount of albumin in the man’s 
urine was reduced relatively but the absolute amount remained un- 
changed ; the circumference of the girl’s abdomen was reduced 3 cm. 
Steinbriick (1881) in his dissertation reported exhaustively on the 
use of Blatta as a diuretic. He examined the earlier literature thor- 
oughly and included detailed case histories of 15 of his own patients 
to whom he had administered Blatta. The diseases included nephritis 
(10 cases), edema of the face and palpitation of the heart (1), tu- 
berculosis (1), mitral insufficiency (1), and two cases with healthy 
kidneys. He was able to verify increased diuresis 14 times in the 15 
patients. In 12 patients with albuminuria there was a reduction of 
albumin in six cases, no effect in two, and in four cases the amount of 
albumin increased. Steinbriick did not observe an increase in sweating 
following doses of Blatta. He concluded that the principal effect of 
powdered cockroach was as a diuretic. 
Bogomolow (1882) reported on 70 more cases of dropsy in which 
