W. Gibbs on the Constitution of Organic Compounds, 28 
and I shall endeavor to show, farther on, that there are other 
reasons for taking this view. Strecker’s elaborate study of the 
bile has shown that cholic and hyocholic acid may each, like 
hippuric acid, be split into glycosin and a new acid. I apply to 
both these acids the theory which I have above developed, and 
consider them rationally represented as follows, 
C2HO2 
eer 2 CeH 
Cholic acid, N Ca3HasOs 
H 
0+HO=Cs2H:sN Oi, 
C2HO2 
Hyocholic acid, N CootnOs ¢ OTHO=OnHisNOw, 
H 
That there are homologous compound molecules having the 
formulas CasH300s and CsvH11Qs, is shown by the existence 
of cholalic and hyocholalic acids, the empirical formulas of which 
are CasH4s0QO10 and CsoHs2010, and which when reduced to 
the type of two equivalents of water become 
. ag i tie” and oe : 02. 
I may here remark that by the action of NOs upon cholic and 
hyocholie acids we ought to obtain two new acids haying the 
formulas 
C2HO2 C2HO2 
co O:=0s2H12014, and tos Oi=Cs1Hss0u. 
H H 
I may further remark, in this connection, that we ought to be 
able to regenerate cholic and hyocholic acids from glycosin and 
cholalic and hyocholalic acids, by processes exactly analogous to 
that employed by Dessaignes in preparing hippuric acid. Thus 
cholalic acid by distillation with perchlorid of phosphorus should 
give chlorhydric acid and chlorid of cholalyl, according to the 
- equation 
tafe 
C1s Hs0010+-PCli==Css H390s.. Cl4+- PO2Cls+ HCl, 
chlorid of cholalyl with glycosin-silver should yield cholic 
and chlorid of silver. As cholalic and hyocholalic acids. 
mologous and have very high equivalents, it is almost cer- 
at they are among the upper members of a complete se- 
ries. Of this series chinovie acid, CssH30Q10, is probably a 
r 
fs 
Hippuric acid.—The formation of this acid by the action of 
chlorid of benzoxyl upon glycosin-zine has already been ex- 
plained upon the ammonium theory as a simple substitution of 
the radical C:1sHsOz for an equivalent of hydrogen. It remains 
to show upon the same theory that the separation of hippuric 
acid into glycosin and benzoic acid may be equally well ac- 
