64 T. S. Hunt on the Constitution of Leucine. 
ciency in the H and N, but those of M. Cahours are ) very close 
approximations. He obtained the no tn A number 
Aposepedine. ei 
Carbon, . . 5519 55:04 5486 55:12 54-79 | 
Hydrogen,. . 986 10-11 10:06 1006 10-04 
Azote,. . . 1063 10:85 1089 1089 | 
The first analyses of MM. Laurent and Gerhardt made upon 
aposepedine, showed a deficiency in the carbon, but by solution in 
nitric acid and evaporation, the salt already deseribed was obtained 
in beautiful erystalline needles, which, dried at 212° F’., corres- 
ponded exactly with the numbers calculated from the formula 
C,,H,,NO,, NO, HO, or in their notation, C,H, 
This salt dissolved i in a little water, mixed with alcohol, and pre- 
cipitated while hot by ammonia, gave leucine in fine white scales, 
entirely inodorous ; the analysis of this gave C 54:6, H 9-9. ‘These 
results establish beyond all doubt the new formula. 
The hydrochloric compound gave Cl 20:6, which corresponds 
to the formula C,H,,NO,, HCl. The nitrate, nitro-leucic 
acid of M. Bracconnot, forms, as that chemist had shown, crys- 
tallizable salts with lime aud magnesia, and the authors have 
described a similar silver-salt. They remark moreover upon the 
fact that the three known alkaloids of this series appear to be 
derived from the same parent substance, for the sarcosine has been 
obtained from creatine which is without doubt a product of the 
transformation of the caaette tissues, and they suggest that 
sarcosine and the two homologues yet unknown, between this 
substance and leucine, may be detected in the products of these 
Ae ace of the animal matters, which yield glyeocoll and 
eucine 
M. Laurent in a late memoir,* has shown that glycocoll may be 
regarded as the amid of an acid which is C,H, O,, and differs” 
from the acetate only by two equivalents of oxygen. For this 
acid he proposes the name of glycocollic; glycocoll will then be 
glycolamic acid. Mr. Horsford, by the action of chlorine upon 
a solution of glycocoll, obtained a substance which gave with — 
chlorid of barinm a ne salt, to which he aseribes the for- 
mula C,H,0O,, BaO,+ but as M. Gerhardt has remarked, ap 
equivalent of the carbon Said be retained by the baryta as é 
a carbonate, and that making a correction for this, the numbers 
obtained lead toC, H,O,, Bac =C, H, BaO, which is that of 
the barytic salt of glycocollic acid. 
This new genus is homologous with the carbonates, and sus- 
tains the same relation to the acetate, as the carbonic C, H, O, 
_ does to formic acid. Carbonic acid is the type of a series of 
ewe 
* Annal. de Chim. et de Phys, May, 1848, p. 111. 
— Sui: ther 1847, p. 3 oT F 
