o- Narcotine, and Sulphate of Morphine. 45 
of that preternatural watchfulfiess, which so often results, both from 
Sulphate of Morphine, and from Opium. From the circumstance 
that Sulphate of Morphine possesses this last mentioned property in an 
eminent degree, and that Narcotine is destitute of it, it follows that 
the same property of Opium is dependent upon its Morphine, and 
not upon its Narcotine. In short, the quality of the nervine opera- 
tion of Narcotine is considerably different from that of Sulphate of 
Morphine, and consequently more or less different from that of 
Opium. 
wth. Narcotine appears to be considerably diaphoretic, and it com- 
monly produces more or less itching of the whole surface, which is 
first perceived, and is most considerable, on the inside of the thighs, 
and about the nose. 
8th. Narcotine is most prominently and most decidedly narcotic. 
' As soon as it begins to produce a decided effect upon the system, 
it Occasions q very peculiar expression of the countenance, which is 
more easily recollected than described. There seems to be a pecu- 
liar elongation of all the features, and a kind of lateral shrinking of 
the whole face, which, together with the effect upon the eyes, and © 
Particularly the contraction of the pupils, more unequivocally indi- 
Cates the operation of a narcotic, than any expression of the counte- 
nance, which is produced within my knowledge by any other agent. 
€ in the early stages of its operation, and before my family 
knew any thing of the experiments, one individual of them after an- 
other, noticed this expression, and made remarks upon it. One said 
bbeared as if about to be attacked with some acute disease—an- 
other inquired if I had got Sick-headache, (to which I am sub- 
Ject,) and each made some comment. Similar remarks were made 
. the other gentlemen. One was met in the street by another phy- 
sician, who immediately pronounced that he was under the influence 
of some active narcotic, 
Nateotine very materially and very greatly reduces the frequency 
of the Pulse ; it allays very effectually certain sorts of cough ; it oc- 
“aSions indistinct vision, or the sensation of a blur before the eyes ; 
and when a person is strongly under its influence, it occasions a con- 
action of the pupils. It produces also a sensation of dryness and 
e'amminess in the mouth, though it appears sufficiently moist to the 
“Yes and it Produces not only a change in the sound of the voice, 
(while 4 person is under its influence,) but likewise very consider- 
able hoarseness, These effects occasionally take place quite early 
